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Testicular cancer is the most common form of cancer in young men ages 15 to 35. It accounts for about 1 percent of all cancer in men, with approximately 7,400 cases diagnosed in the United States every year. It is much more common in white males than in black males. The incidence of testicular cancer has risen over the last century, although the reason for this increase is not clear.

Risk factors for testicular cancer include undescended testicle (cryptorchidism), a prior history of cancer in one testicle (the opposite testicle is at increased risk) and family history of testicular cancer. Testicular cancer is also sometimes linked to other rare conditions in which the testes do not develop normally.

FTC is just one of the many Clinical Genetics Branch (CGB) research areas that conduct clinical, genetic, and epidemiologic studies of individuals at high risk of cancer in order to improve our understanding of cancer etiology and to advance clinical care.